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Human IMP1/IMPA1 Recombinant Protein (RPES1485)

SKU:
RPES1485
Product Type:
Recombinant Protein
Species:
Human
€357
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Description

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Human IMP1/IMPA1 Recombinant Protein

Inositol monophosphatase 1 (IMPA1) is a myo-inositol monophosphate dephosphorylating enzyme that gives rise to free myo-inositol, a precursor of phosphatidylinositol, and therefore regulates intracellular cellular signalling by producing the second messengers myoinosit 1,4,5-triphosphate and diacylglycerol. IMPA1 has phosphatase activity that is reliant on magnesium and is inhibited by therapeutic lithium doses. Lithium's anti-manic and anti-depressive effects in bipolar patients may be linked to the inhibition of inositol monophosphate hydroylosis, which leads to a reduction in inositol for phosphatidylinositol synthesis. FOR IMPA1 pseudogenes may also be identified on chromosome 8q21.13. IMPA1 is a gene that has been linked to mental retardation, autosomal recessive 59, and bipolar disorder. Human IMP1/IMPA1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.