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Human ILRAcP/IL1R3 Recombinant Protein (RPES0989)

SKU:
RPES0989
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology
€150
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Description

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Human ILRAcP/IL1R3 Recombinant Protein

Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1?; IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1; TOLLIP; MYD88; and IRAK1 or IRAK2. In addition; IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.

Product Name:Human ILRAcP/IL1R3 Recombinant Protein (RPES0989)
Product Code:RPES0989
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Interleukin-1 Receptor Accessory Protein, IL-1 Receptor Accessory Protein, IL-1RAcP, Interleukin-1 Receptor 3, IL-1R-3, IL-1R3, IL1RAP, C3orf13, IL1R3
Accession:Q9NPH3
Sequence:Ser21-Gln356
Fusion tag:C-Fc-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Interleukin-1 Receptor Accessory Protein is produced by our Mammalian expression system and the target gene encoding Ser21-Gln356 is expressed with a Fc; 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:39.7 kDa
AP Mol Mass:82 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4 .
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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