Human ILR8/IL1RAPL1 Recombinant Protein (RPES1830)
- SKU:
- RPES1830
- Product Type:
- Recombinant Protein
- Species:
- Human
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Description
system_update_altDatasheet
Human ILR8/IL1RAPL1 Recombinant Protein
Interleukin-1 receptor accessory protein-like 1; also known as IL1RAPL1; can be detected at low levels in heart; skeletal muscle; ovary; skin; amygdala; caudate nucleus; corpus callosum; hippocampus; substantia nigra and thalamus. IL1RAPL1 functions as a homodimer; it interacts with NCS1; PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation; it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.
| Product Name: | Human ILR8/IL1RAPL1 Recombinant Protein (RPES1830) |
| Product Code: | RPES1830 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Interleukin-1 Receptor Accessory Protein-Like 1, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, Oligophrenin-4, Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2, TIGIRR-2, X-Linked Interleukin-1 Receptor Accessory Protein-Like 1, IL1RAPL1, OPHN4 |
| Accession: | Q9NZN1 |
| Sequence: | Leu19-Thr357 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human IL-1R8 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr357 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 68 kDa |
| AP Mol Mass: | 80-100 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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