Interleukin-1 alpha (IL1-alpha) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1-alpha and IL1-beta that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1-alpha is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. A wide range of cells, including osteoblasts, monocytes, and macrophages, are induced to express IL1-alpha in response to stimulation. IL1-alpha possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses. Human ILA/IL Alpha Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Recombinant Human IL-1A is produced by our E.coli expression system and the target gene encoding Ser113-Ala271 is expressed.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
18 kDa
AP Mol Mass:
17 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
