Recombinant Human IL-7 Protein(Sumo Tag) (RPES8024)
- SKU:
- RPES8024
- Size:
- 20μg
- Tag:
- N-Sumo
- Reactivity:
- Human
- Expression Host:
- E.coli
- Accession:
- P13232
Description
| Product Name: | Recombinant Human IL-7 Protein (Sumo Tag) |
| SKU: | RPES8024 |
| Size: | 20μg |
| Tag: | N-Sumo |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | P13232 |
| Sequence: | Asp26-His177 |
| Calculated Molecular Weight: | 32.6 kDa |
| Observed Molecular Weight: | 35 kDa |
| Synonyms: | IL 7, IL-7, Il7, IL7, Interleukin 7, Interleukin-7, LP-1, Lymphopoietin 1 |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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