Recombinant Human GITR Ligand/TNFSF18 Protein (Fc Tag) (RPES8377)
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- SKU:
- RPES8377
- Size:
- 20μg
- Tag:
- C-Fc
- Reactivity:
- Human
- Expression Host:
- Mammalian
- Accession:
- Q9UNG2
Description
| Product Name: | Recombinant Human GITR Ligand/TNFSF18 Protein (Fc Tag) |
| SKU: | RPES8377 |
| Size: | 20μg |
| Tag: | C-Fc |
| Reactivity: | Human |
| Expression Host: | Mammalian |
| Accession: | Q9UNG2 |
| Sequence: | Glu52-Ser177 |
| Calculated Molecular Weight: | 38.8 kDa |
| Observed Molecular Weight: | 40 kDa |
| Synonyms: | UNQ, PRO, Tnfsf, Activation-inducible TNF-related ligand, Glucocorticoid-induced TNF-related ligand, hGITRL, TNLG2A, AITRL, GITRL, TL6, TNFSF18, UNQ149, PRO175, Activation inducible TNF related ligand, AITR ligand, AITR ligand|GITR ligand|glucocorticoid-induced TNFR-related protein ligand, GITR ligand, Glucocorticoid induced TNF related ligand, Glucocorticoid induced TNFR related protein ligand, MGC138237, TNF18, Tumor necrosis factor (ligand) superfamily member 18, Tumor necrosis factor ligand 2A, Tumor necrosis factor ligand superfamily member 18 |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thoμght to be important for interaction between T lymphocytes and endothelial cells.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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