null

Recombinant Human GDNFR-alpha-1/GFRA1 Protein (RPCB0258)

SKU:
RPCB0258
Size:
20µg
Tag:
C-hFc&His
Reactivity:
Human
Expression Host:
HEK293 cells
€89
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human GDNFR-alpha-1/GFRA1 Protein
SKU:RPCB0258
Size:20µg
Tag:C-hFc&His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human GDNFR-alpha-1/GFRA1 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 1.0 EU/μg of the protein by LAL method.
Purity:> 80% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Gene ID:2674

This protein is a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P56159
Product ImageRecombinant Human GDNFR- alpha-1/GFRA1 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 100 kDa.
Product ImageImmobilized recombinant Human GDNF at 1 μg/mL (100 μL/well) can bind Human GFRA1 with a linear range of 2-332ng/mL.

Related Products