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Recombinant Human Gamma-glutamyl hydrolase/GGH Protein (RPCB0111)

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SKU:
RPCB0111
Size:
10µg
Tag:
N-His
Reactivity:
Human
€139

Description

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Product Name:Recombinant Human Gamma-glutamyl hydrolase/GGH Protein
SKU:RPCB0111
Size:10µg
Tag:N-His
Reactivity:Human
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human Gamma-glutamyl hydrolase/GGH Protein , tested reactivity inE. coliand has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 0.1 EU/μg of the protein by LAL method.
Purity:> 95% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of 20mM HEPES, 150mM NaCl, 1mM TCEP, pH 8.0.
Gene ID:8836

Gamma-glutamyl hydrolase/GGH regulates intracellular folates and antifolates such as methotrexate (MTX) for proper nucleotide biosynthesis and antifolate-induced cytotoxicity, respectively. GGH is a ubiquitously-expressed enzyme that regulates intracellular folate metabolism for cell proliferation, DNA synthesis, and repair. cytoplasmic GGH might play a relevant role in the development and progression of invasive breast cancer.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q92820
Product ImageRecombinant Human Gamma- glutamyl hydrolase/GGH Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.

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