The Galectin family of proteins; with specificity for Nacetyllactosamine containing glycoproteins; consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also have hemagglutination activity, which is due to their bivalent carbohydrate binding capabilities. Galectins are active both intracellularly and extracellularly. Despite the fact that they are primarily found in the cytoplasm and lack a classical signal peptide, they can be secreted by one or more as yet unknown non-classical secretory pathways. Adhesion; migration; polarity; chemotaxis; proliferation; apoptosis; and differentiation are just a few of the many cellular functions that they influence. Galectins may be involved in a variety of pathological conditions, including autoimmune diseases, allergies, inflammation, tumor cell metastasis, atherosclerosis, and diabetic complications. Human Galectin-7/LGALS7 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human Galectin-7/LGALS7 Recombinant Protein (RPES4675)
Measured by its ability to agglutinate human red blood cells.
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Galectin-7 is produced by our E.coli expression system and the target gene encoding Met1-Phe136 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
14.9 kDa
AP Mol Mass:
14 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
