Recombinant Human FKBP1A/FKBP12 Protein (RPCB0142)
- SKU:
- RPCB0142
- Size:
- 10µg
- Tag:
- No tag
- Reactivity:
- Human
- Expression Host:
- E. coli
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Description
Product Name: | Recombinant Human FKBP1A/FKBP12 Protein |
SKU: | RPCB0142 |
Size: | 10µg |
Tag: | No tag |
Reactivity: | Human |
Expression Host: | E. coli |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human FKBP1A/FKBP12 Protein , tested reactivity inE. coliand has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 0.1 EU/μg of the protein by LAL method. |
Purity: | > 90% by SDS-PAGE. |
Formulation: | Lyophilized from a 0.22 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.Contact us for customized product form or formulation. |
Gene ID: | 2280 |
The protein is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor.
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Swiss-Prot: | P62942 |