Human FGF9/FGF9 Recombinant Protein (RPES3911)
- SKU:
- RPES3911
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Growth Factors & Cytokines
Frequently bought together:
Description
system_update_altDatasheet
Human FGF9/FGF9 Recombinant Protein
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile acid absorption. It has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. FGF19 can be considered as a regulator of energy expenditure.
| Product Name: | Human FGF9/FGF9 Recombinant Protein (RPES3911) |
| Product Code: | RPES3911 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Fibroblast growth factor 19, FGF-19, FGF19 |
| Accession: | O95750 |
| Sequence: | Phe27-Lys216 |
| Fusion tag: | N-6His |
| Activity: | Immobilized Human FGF-19-His at 2µg/ml(100 ?l/well) can bind Human FGFR3-Fc(Cat: PKSH033678). The ED50 of Human FGF-19-His is 3.1135 ug/ml. |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fibroblast growth factor 19 is produced by our E.coli expression system and the target gene encoding Phe27-Lys216 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 23.5 kDa |
| AP Mol Mass: | 24 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB?150mM NaCl,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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