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Recombinant Human Fc-gamma RIII alpha/CD16a(F176V) Protein (RPCB1218)

SKU:
RPCB1218
Size:
10µg
Tag:
C-His
Reactivity:
Human
Expression Host:
HEK293 cells
€129

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human Fc-gamma RIII alpha/CD16a (F176V) Protein
SKU:RPCB1218
Size:10µg
Tag:C-His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human Fc-gamma RIII alpha/CD16a(F176V) Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<1EU/μg
Purity:> 95% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:2214（F176V）

This protein is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. The protein is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P08637
Product ImageRecombinant Human Fc-gamma RIII alpha/CD16a(F176V) Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 38-52kDa.

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