Human FBPase 1/FBP1 Recombinant Protein (RPES3762)
- SKU:
- RPES3762
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Metabolism
Frequently bought together:
Description
system_update_altDatasheet
Human FBPase 1/FBP1 Recombinant Protein
Fructose-1;6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1;6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.
| Product Name: | Human FBPase 1/FBP1 Recombinant Protein (RPES3762) |
| Product Code: | RPES3762 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Fructose-1,6-bisphosphatase 1,D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,FBP,FBPase 1 |
| Accession: | P09467 |
| Sequence: | Ala2-Gln338 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fructose-1;6-Bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 37.8 kDa |
| AP Mol Mass: | 35 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl;200mM NaCl;1mM DTT;10% Glycerol;pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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