Human ERP57/PDIA3 Recombinant Protein (His Tag) (RPES3066)
- SKU:
- RPES3066
- Product Type:
- Recombinant Protein
- Species:
- Human
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Description
system_update_altDatasheet
Human ERP57/PDIA3 Recombinant Protein
PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
| Product Name: | Human ERP57/PDIA3 Recombinant Protein (RPES3066) |
| Product Code: | RPES3066 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | PDIA3 protein,Protein disulfide-isomerase A3,58 kDa glucose-regulated protein,Disulfide isomerase ER-60,ER protein 57 |
| Accession: | P30101 |
| Sequence: | Ser25-Leu505 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Protein Disulfide-Isomerase A3 is produced by our Mammalian expression system and the target gene encoding Ser25-Leu505 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 55.3 kDa |
| AP Mol Mass: | 60 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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