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Recombinant Human ERBB2/HER2/CD340 (489-630) Protein (RPCB0582)

SKU:
RPCB0582
Size:
100µg
Tag:
C-His&Avi
Reactivity:
Human
Expression Host:
E. coli
€449

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human ERBB2/HER2/CD340 (489-630) Protein
SKU:RPCB0582
Size:100µg
Tag:C-His&Avi
Reactivity:Human
Expression Host:E. coli
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human ERBB2/HER2/CD340 (489-630) Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 1 EU/μg of the protein by LAL method
Purity:> 95% by SDS-PAGEï¼›> 95% by HPLC
Formulation:Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene ID:2064

ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P04626-1
Product ImageHuman Her2 Domain 4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Product ImageThe purity of Human Her2 Domain 4 is greater than 95% as determined by SEC-HPLC.

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