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Human DPEP2 Recombinant Protein (RPES3987)

SKU:
RPES3987
Product Type:
Recombinant Protein
Species:
Human
€540
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Description

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Human DPEP2 Recombinant Protein

DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.

Product Name:Human DPEP2 Recombinant Protein (RPES3987)
Product Code:RPES3987
Size:20µg
Species:Human
Expressed Host:HEK293 Cells
Synonyms:MBD2
Accession:AAH24021.1
Sequence:Met 1-Ser376
Fusion tag:C-Fc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human DPEP2 (AAH24021.1) (Met1-Ser376) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:65 kDa
AP Mol Mass:43-49 kDa
Formulation:Lyophilized from sterile PBS, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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