null

Human Cyclophilin C/PPIC Recombinant Protein (RPES1562)

SKU:
RPES1562
Product Type:
Recombinant Protein
Species:
Human
€357
Frequently bought together:

Description

system_update_altDatasheet

Human Cyclophilin C/PPIC Recombinant Protein

Cyclophilin C is an enzyme (EC 5.2.1.8) found in both prokaryotes and eukaryotes that interconverts the cis and trans isomers of peptide bonds with the amino acid proline. Proline has an unusually conformationally restrained peptide bond due to its cyclic structure with its side chain bonded to its secondary amine nitrogen. Most amino acids have a strong energetic preference for the trans peptide bond conformation due to steric hindrance, but prolines unusual structure stabilizes the cis form so that both isomers are populated under biologically relevant conditions. Proteins with prolyl isomerase activity include cyclophilin, FKBPs, and parvulin, although larger proteins can also contain prolyl isomerase domains.

Product Name:Human Cyclophilin C/PPIC Recombinant Protein (RPES1562)
Product Code:RPES1562
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Peptidyl-Prolyl Cis-Trans Isomerase C, PPIase C, Cyclophilin C, Rotamase C, PPIC, CYPC
Accession:P45877
Sequence:Lys31-Asp182
Fusion tag:N-Trx
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Peptidyl-Prolyl cis-trans Isomerase C is produced by our E.coli expression system and the target gene encoding Lys31-Asp182 is expressed with a Trx, 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:33.8 kDa
AP Mol Mass:34 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH 7.4.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Related Products