Human Cyclophilin B/PPIB Recombinant Protein (RPES0593)
- SKU:
- RPES0593
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human Cyclophilin B/PPIB Recombinant Protein
Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.
Product Name: | Human Cyclophilin B/PPIB Recombinant Protein (RPES0593) |
Product Code: | RPES0593 |
Size: | 10µg |
Species: | Human |
Expressed Host: | Human Cells |
Synonyms: | CYP-S1, CYPB, HEL-S-39, OI9, SCYLP |
Accession: | P23284 |
Sequence: | Asp34-Ala212 |
Fusion tag: | C-His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Cyclophilin B is produced by our Mammalian expression system and the target gene encoding Asp34-Ala212 is expressed with a 6His tag at the C-terminus. |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Mol Mass: | 20.9 kDa |
AP Mol Mass: | 21 kDa |
Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |