Recombinant Human CX3CL1/Fractalkine Protein (RPCB1159)
- SKU:
- RPCB1159
- Size:
- 10µg
- Tag:
- C-6His
- Reactivity:
- Human
- Expression Host:
- Pichia
Description
| Product Name: | Recombinant Human CX3CL1/Fractalkine Protein |
| SKU: | RPCB1159 |
| Size: | 10µg |
| Tag: | C-6His |
| Reactivity: | Human |
| Expression Host: | Pichia |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human CX3CL1/Fractalkine Protein , tested reactivity inPichiaand has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | ＜0.1EU/μg |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 6376 |
Fractalkine or Chemokine (C-X3-C motif) ligand 1 (CX3CL1) is a member of the CX3C chemokine family. Fractalkine / CX3CL1 is a unique chemokine that functions not only as a chemoattractant but also as an adhesion molecule and is expressed on endothelial cells activated by proinflammatory cytokines, such as interferon-gamma and tumor necrosis factor-alpha. Fractalkine/CX3CL1 is expressed in a membrane-bound form on activated endothelial cells and mediates attachment and firm adhesion of T cells, monocytes and NK cells. Fractalkine / CX3CL1 is associated with dendritic cells (DC) in epidermis and lymphoid organs. The fractalkine receptor, CX3CR1, is expressed on cytotoxic effector lymphocytes, including natural killer (NK) cells and cytotoxic T lymphocytes, which contain high levels of intracellular perforin and granzyme B, and on macrophages. Soluble fractalkine causes migration of NK cells, cytotoxic T lymphocytes, and macrophages, whereas the membrane-bound form captures and enhances the subsequent migration of these cells in response to secondary stimulation with other chemokines.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P78423 |
 | Recombinant Human CX3CL1/Fractalkine Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 35-35 kDa. |
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