Recombinant Human CRTAM Protein (His Tag) (RPES8279)
- SKU:
- RPES8279
- Size:
- 20μg
- Tag:
- C-His
- Reactivity:
- Human
- Expression Host:
- Mammalian
- Accession:
- O95727
Frequently bought together:
Description
| Product Name: | Recombinant Human CRTAM Protein (His Tag) |
| SKU: | RPES8279 |
| Size: | 20μg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | Mammalian |
| Accession: | O95727 |
| Sequence: | Ser18-Gly287 |
| Calculated Molecular Weight: | 29.5 kDa |
| Observed Molecular Weight: | 55-65 kDa |
| Synonyms: | CD355, Class I MHC restricted T cell associated molecule, Class-I MHC-restricted T-cell-associated molecule, CRTAM, CRTAM, Cytotoxic and regulatory T cell molecule, Cytotoxic and regulatory T-cell molecule |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A, MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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