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Human Contactin 2/CNTN2 Recombinant Protein (RPES1005)

SKU:
RPES1005
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology
$283
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Description

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Human Contactin 2/CNTN2 Recombinant Protein

Contactin-2 (CNTN2) is encoded by the CNTN2 gene,which belongs to the immunoglobulin superfamily and contactin family. It contains 4 fibronectin type-III domains and 6 Ig-like C2-type domains. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. CNTN2 may play a role in the formation of axon connections in the developing nervous system. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.

Product Name:Human Contactin 2/CNTN2 Recombinant Protein (RPES1005)
Product Code:RPES1005
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Contactin-2, Axonal glycoprotein TAG-1, Axonin-1, Transient axonal glycoprotein 1, CNTN2, AXT, TAG1, TAX1
Accession:Q02246
Sequence:Ser31-Asn1012
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Transient axonal glycoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Asn1012 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:108.7 kDa
AP Mol Mass:110-140 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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