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Human Collectin1/COLEC11 Recombinant Protein (RPES0824)

SKU:
RPES0824
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology
€212
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Description

system_update_altDatasheet

Human Collectin1/COLEC11 Recombinant Protein

Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compared to mannose. Collectin-11 binds lipopolysaccharides (LPS). It also involved in fundamental development serving as a guidance cue for neural crest cell migration. Defects in Collectin-11 are the cause of 3MC syndrome type 2 (3MC2).

Product Name:Human Collectin1/COLEC11 Recombinant Protein (RPES0824)
Product Code:RPES0824
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Collectin-11, Collectin Kidney Protein 1, CL-K1, COLEC11
Accession:Q9BWP8
Sequence:Gln26-Met271
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Collectin-11 is produced by our Mammalian expression system and the target gene encoding Gln26-Met271 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:27.1 kDa
AP Mol Mass:30 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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