CLM-9, also known as TREM4, is a receptor that belongs to the TREM family. TREM receptors control the function of several types of immune system cells, including neutrophils, monocyte/macrophages, microglia, and dendritic cells. L-selectin may induce the rolling of leukocytes, which is aided by the presence of CLM-9. It binds SELL in a calcium-dependent manner. It also binds to lymphocytes, indicating that it is involved in lymphocyte adherence. The CLM-9 main transcript is highly expressed in the human heart, skeletal muscle, and placenta. Analysis has revealed that the mouse protein is expressed in capillary endothelial cells. Human CLM-9 binds to human IgA2 and mouse IgM receptors. Human CLM-9/TREM4 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human CLM-9/TREM4 Recombinant Protein (RPES0193)
Product Code:
RPES0193
Size:
20µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
CMRF35-Like Molecule 9, CLM-9, CD300 Antigen-Like Family Member G, Triggering Receptor Expressed on Myeloid Cells 4, TREM-4, CD300g, CD300LG, CLM9, TREM4,NEPMUCIN
Accession:
AAH25395.1
Sequence:
Met 1-Arg247
Fusion tag:
Endotoxin:
<1.0 EU per µg of the protein as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human CD300LG (AAH25395.1)(Met1-Arg247) was expressed with six amino acids (LEVLFQ) at the C-terminus was expressed and purified.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
25.5 kDa
AP Mol Mass:
61-66 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
