Human Chymotrypsin C Recombinant Protein (RPES2814)
- SKU:
- RPES2814
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
system_update_altDatasheet
Human Chymotrypsin C Recombinant Protein
Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity; but prefers tocleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas; and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
Product Name: | Human Chymotrypsin C Recombinant Protein (RPES2814) |
Product Code: | RPES2814 |
Size: | 10µg |
Species: | Human |
Expressed Host: | Human Cells |
Synonyms: | Chymotrypsin-C, Caldecrin, CTRC, CLCR |
Accession: | Q99895 |
Sequence: | Cys17-Leu268 |
Fusion tag: | C-6His |
Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
Protein Construction: | Recombinant Human Chymotrypsin-C is produced by our Mammalian expression system and the target gene encoding Cys17-Leu268 is expressed with a 6His tag at the C-terminus. |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Mol Mass: | 29.0 kDa |
AP Mol Mass: | 35 kDa |
Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 150mM NaCl; pH 8.0. |
Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |