Glycoprotein hormones alpha chain, also known as CGA, belongs to the glycoprotein hormones subunit alpha family. The subunit of CGA is a heterodimer consists of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. It has positive regulation of cell migration, cell proliferation and transcription from RNA polymerase II promoter and participates in the peptide hormone processing and signal transduction.
Product Name:
Human CGA&CGB3 Heterodimer Recombinant Protein (RPES2451)
Product Code:
RPES2451
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Beta-Nerve Growth Factor, Beta-NGF, NGF, NGFB
Accession:
P01215&P0DN86
Sequence:
Ala25-Ser116&Ser21-Gln165
Fusion tag:
C-Flag,C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human CGA&CGB3 Heterodimer is produced by our Mammalian expression system and the target gene encoding Ala25-Ser116&Ser21-Gln165 is expressed with a Flag tag at the C-terminus, 6His tag at the C-terminus.
Purity:
> 90% as determined by reducing SDS-PAGE.
Mol Mass:
11.6&16.6 kDa
AP Mol Mass:
22&30-35 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS,pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
