The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR); anectins and nectin-like protein family member serve to mediate cell-cell adhesion; cell migration; with the presence of an additional receptor; CD96. CD96 promotes NK cell adhesion to target cells expressing PVR; stimulates cytotoxicity of activated NK cells; and mediates acquisition of PVR from target cells.
Product Name:
Human CD96 Recombinant Protein (RPES4476)
Product Code:
RPES4476
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
T-cell surface protein tactile, Cell surface antigen CD96, T cell-activated increased late expression protein, CD96
Accession:
P40200-2
Sequence:
Val22-Met503
Fusion tag:
C-His
Activity:
Immobilized Human PVR-His(Cat: PKSH033563) at 10µg/ml(100 ?l/well) can bind Biotinylated Human CD96-His. The ED50 of Human CD96-His is 27.54µg/mL.
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human CD96 is produced by our Mammalian expression system and the target gene encoding Val22-Met503 is expressed with a 6His tag at the C-terminus.
Purity:
> 90% as determined by reducing SDS-PAGE.
Mol Mass:
54.4 kDa
AP Mol Mass:
120-130 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
