Description
Product Name: | Recombinant Human CD30 Protein (Fc Tag) |
SKU: | RPES8286 |
Size: | 20μg |
Tag: | C-Fc |
Reactivity: | Human |
Expression Host: | Mammalian |
Accession: | P28908 |
Sequence: | Phe19-Lys379 |
Calculated Molecular Weight: | 64.6 kDa |
Observed Molecular Weight: | 80-100 kDa |
Synonyms: | CD 30, CD30, CD30 antigen, CD30L receptor, Cytokine receptor CD30, D1S166E, KI 1, KI 1 antigen, Ki-1 antigen, KI1, Lymphocyte activation antigen CD30, TNFRSF 8, Tnfrsf8, TNR8, Tumor necrosis factor receptor superfamily member 8 |
Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
Purity: | > 90% as determined by reducing SDS-PAGE. |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with an this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Bio-activity: | Not validated for activity |
Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |