Human CD27/TNFRSF7 Recombinant Protein (RPES5085)
- SKU:
- RPES5085
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Death
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Description
system_update_altDatasheet
Human CD27/TNFRSF7 Recombinant Protein
CD27 antigen is also known as CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7; T14 and TNFRSF7. In humans; it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70; and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
| Product Name: | Human CD27/TNFRSF7 Recombinant Protein (RPES5085) |
| Product Code: | RPES5085 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | S152,S152. LPFS2,S152.LPFS2,T14,TNFRSF7,Tp55 |
| Accession: | P26842 |
| Sequence: | Thr 21-Ile192 |
| Fusion tag: | C-Fc-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human CD27 is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a Fc; 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 47.2 kDa |
| AP Mol Mass: | 60 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Tris;150mM NaCl; pH 8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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