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Recombinant Human CD27 Ligand/TNFSF7/CD70 (C-mFc)

SKU:
RPES6210
Product Type:
Recombinant Protein
Species:
Human
€229
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Description

Product Name:Recombinant Human CD27 Ligand/TNFSF7/CD70 (C-mFc)
Product Code:RPES6210
Size:10µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:CD70 antigen, CD70, CD27 ligand, Tumor necrosis factor ligand superfamily member 7, CD27LG, TNFSF7, CD27L
Mol Mass:43 kDa
AP Mol Mass:50-60 kDa
Tag:C-mFc
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Gln45-Pro193
Accession:P32970
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

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