Recombinant Human CCL5/RANTES Protein (RPCB1777)
- SKU:
- RPCB1777
- Size:
- 10µg
- Tag:
- C-6His
- Reactivity:
- Human
- Expression Host:
- E. coli
Description
| Product Name: | Recombinant Human CCL5/RANTES Protein |
| SKU: | RPCB1777 |
| Size: | 10µg |
| Tag: | C-6His |
| Reactivity: | Human |
| Expression Host: | E. coli |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human CCL5/RANTES Protein , tested reactivity inE. coliand has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1EU/μg |
| Purity: | > 97% by SDS-PAGE. |
| Formulation: | Supplied as a 0.22 μm filtered solution in PBS, pH 7.4. |
| Gene ID: | 6352 |
Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
| Storage: | Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
| Swiss-Prot: | P13501 |
 | Recombinant Human CCL5/RANTES Protein was determined by SDS- PAGE with Coomassie Blue, showing a band at 10-15 kDa. |
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