Recombinant Human CCL27/CTACK Protein(Sumo Tag) (RPES8106)
- SKU:
- RPES8106
- Size:
- 20μg
- Tag:
- N-Sumo
- Reactivity:
- Human
- Expression Host:
- E.coli
- Accession:
- Q9Y4X3
Description
| Product Name: | Recombinant Human CCL27/CTACK Protein (Sumo Tag) |
| SKU: | RPES8106 |
| Size: | 20μg |
| Tag: | N-Sumo |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | Q9Y4X3 |
| Sequence: | Phe25-Gly112 |
| Calculated Molecular Weight: | 22.6 kDa |
| Observed Molecular Weight: | 28 kDa |
| Synonyms: | CCL, SCYA, CCL27, ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27, CC Chemokine ILC, C-C Motif Chemokine 27, Cutaneous T-Cell-Attracting Chemokine, IL-11 R-Alpha-Locus Chemokine, Skinkine, Small-Inducible Cytokine A27, Chemokine (C-C motif) ligand 27, Cutaneous T cell attracting chemokine, IL 11 R alpha locus chemokine, member 27, Small inducible cytokine A27, small inducible cytokine subfamily A (Cys-Cys) |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
CCL27/CTACK, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27/CTACK is chemotactic for skin-associated memory T lymphocytes. CCL27/CTACK may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27/CTACK plays a pivotal role in establishing the inflammatory infiltrate characteristic for common inflammatory skin diseases. Throμgh binding to the chemokine receptor 1 (CCR1), CCL27/CTACK mediates inflammation by promoting lymphocyte migration into the skin.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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