Human CAMK1/CaMKI-alpha Recombinant Protein (RPES4007)
- SKU:
- RPES4007
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Cycle
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Description
system_update_altDatasheet
Human CAMK1/CaMKI-alpha Recombinant Protein
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed. CAMK1 is phosphorylated by CaMKK1 and CaMKK2 on Thr-177. CAMK1 regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization, and neurite outgrowth. CAMK1 plays a role in K+ and ANG2-mediated regulation of the aldosterone synthase (CYP11B2) to produce aldosterone in the adrenal cortex.
| Product Name: | Human CAMK1/CaMKI-alpha Recombinant Protein (RPES4007) |
| Product Code: | RPES4007 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Calcium/Calmodulin-Dependent Protein Kinase Type 1, CaM Kinase I, CaM-KI, CaM Kinase I Alpha, CaMKI-Alpha, CAMK1 |
| Accession: | Q14012 |
| Sequence: | Met1-Leu370 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human CAMK1 is produced by our Mammalian expression system and the target gene encoding Met1-Leu370 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 42.3 kDa |
| AP Mol Mass: | 42 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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