Human C1QBP Recombinant Protein (RPES2490)
- SKU:
- RPES2490
- Product Type:
- Recombinant Protein
- Species:
- Human
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Description
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Human C1QBP Recombinant Protein
Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.
| Product Name: | Human C1QBP Recombinant Protein (RPES2490) |
| Product Code: | RPES2490 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial, ASF/SF2-Associated Protein p32, Glycoprotein gC1qBP, C1qBP, Hyaluronan-Binding Protein 1, Mitochondrial Matrix Protein p32, gC1q-R Protein, p33, C1QBP, GC1QBP, HABP1, SF2P32,gC1qR |
| Accession: | NP_001203.1 |
| Sequence: | Leu74-Gln282 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Hyaluronic Acid-binding Protein is produced by our E.coli expression system and the target gene encoding Leu74-Gln282 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 85 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 24.9 kDa |
| AP Mol Mass: | 34 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris, 20% Glycerol, 1mM DTT, pH 7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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