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Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His) (RPES6252)

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SKU:
RPES6252
Product Type:
Recombinant Protein
Species:
Human
€179

Description

Product Name:Recombinant Human C-X-C Motif Chemokine 6/CXCL6 (C-6His)
Product Code:RPES6252
Size:10µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:C-X-C Motif Chemokine 6, Chemokine Alpha 3, CKA-3, Granulocyte Chemotactic Protein 2, GCP-2, Small-Inducible Cytokine B6, CXCL6, GCP2, SCYB6
Mol Mass:9.35 kDa
AP Mol Mass:13 kDa
Tag:C-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Gly38-Asn114
Accession:P80162
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in t
Reconstitution:Please refer to the printed manual for detailed information.
Background:Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell-derived neutrophil attractant-78 (ENA-78)/CXCL5. The human CXCL6 gene has been cloned and is physically mapped to the CXC chemokine locus on chromosome 4. Mature human CXCL6 is a 75 amino acid (aa) protein with a predicted molecular weight of approximately 8 kDa. Human CXCL6 shares 60% and 67% aa identity with mouse and bovine CXCL6, respectively.

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