Recombinant Human BMP-2 Protein(Gst Tag) (RPES8032)
- SKU:
- RPES8032
- Size:
- 20μg
- Tag:
- N-Gst
- Reactivity:
- Human
- Expression Host:
- E.coli
- Accession:
- P12643
Description
| Product Name: | Recombinant Human BMP-2 Protein (Gst Tag) |
| SKU: | RPES8032 |
| Size: | 20μg |
| Tag: | N-Gst |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | P12643 |
| Sequence: | Gln283-Arg396 |
| Calculated Molecular Weight: | 38 kDa |
| Observed Molecular Weight: | 42 kDa |
| Synonyms: | BDA2, BMP-2, BMP-2A, Bmp2, BMP2, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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