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Recombinant Human beta Defensin 3/DEFB103A Protein (RPCB1906)

SKU:
RPCB1906
Size:
100µg
Tag:
N-His
Reactivity:
Human
Expression Host:
E. coli
€799

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human beta Defensin 3/DEFB103A Protein
SKU:RPCB1906
Size:100µg
Tag:N-His
Reactivity:Human
Expression Host:E. coli
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human beta Defensin 3/DEFB103A Protein , tested reactivity inE. coliand has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:Please contact us for more information.
Purity:>95% as determined by SDS-PAGE
Formulation:Lyophilized from a 0.22 μm filtered solution of 50mM Tris, 0.3% Ttiton X-100, 0.3% SKL, pH 8.5.
Gene ID:55894

Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. It is also expressed in salivary gland, bone marrow, colon, stomach, polyp and larynx. However, in small intestine, it cannot be detected. Defensin has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. Beta-defensin 3 kills multiresistant S.aureus and vancomycin-resistent E.faecium. It has no significant hemolytic activity.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P81534
Product ImageRecombinant Human beta Defensin 3/DEFB103A Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 13 kDa.

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