Recombinant Human Beclin-1 Protein(Trx Tag) (RPES8060)
- SKU:
- RPES8060
- Size:
- 20μg
- Tag:
- N-Trx
- Reactivity:
- Human
- Expression Host:
- E.coli
- Accession:
- Q14457
Description
| Product Name: | Recombinant Human Beclin-1 Protein (Trx Tag) |
| SKU: | RPES8060 |
| Size: | 20μg |
| Tag: | N-Trx |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | Q14457 |
| Sequence: | Thr141-Lys450 |
| Calculated Molecular Weight: | 54 kDa |
| Observed Molecular Weight: | 60 kDa |
| Synonyms: | APG6, ATG 6, ATG6, ATG6 autophagy related 6 homolog, Bcl-2-interacting protein beclin, Beclin 1 (coiled coil moesin like BCL2 interacting protein), Beclin 1 autophagy related, Beclin-1, Beclin1, BECN 1, Becn1, BECN1, Coiled coil myosin like BCL2 interacting protein, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197, VPS 30, VPS30 |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
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