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Recombinant Human B7-H3 (4Ig)/B7-H3b/CD276 Protein (RPCB0581)

SKU:
RPCB0581
Size:
100µg
Tag:
C-His&Avi
Reactivity:
Human
Expression Host:
E. coli
$491

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Recombinant Human B7-H3 (4Ig)/B7-H3b/CD276 Protein
SKU:RPCB0581
Size:100µg
Tag:C-His&Avi
Reactivity:Human
Expression Host:E. coli
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human B7-H3 (4Ig)/B7-H3b/CD276 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 1 EU/μg of the protein by LAL method
Purity:> 95% by SDS-PAGEï¼›> 95% by HPLC
Formulation:Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene ID:80381

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig?B7?H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q5ZPR3-1
Product ImageHuman B7-H3 (4Ig) on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Product ImageThe purity of Human B7-H3 (4Ig) is greater than 95% as determined by SEC-HPLC.

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