null

Human ATG10 Recombinant Protein (RPES3103)

SKU:
RPES3103
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Autophagy
€357
Frequently bought together:

Description

system_update_altDatasheet

Human ATG10 Recombinant Protein

Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.