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Human ASS1 Recombinant Protein (RPES3002)

SKU:
RPES3002
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism
€357
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Description

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Human ASS1 Recombinant Protein

Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullinemia (CTLN1), an autosomal recessive disease which is characterized by severe vomiting spells and mental retardation.

Product Name:Human ASS1 Recombinant Protein (RPES3002)
Product Code:RPES3002
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Argininosuccinate Synthase, Citrulline--Aspartate Ligase, ASS1, ASS
Accession:P00966
Sequence:Met 1-Lys412
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Argininosuccinate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys412 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:42.8 kDa
AP Mol Mass:50 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, 50mM Imidazole, 1mM DTT, 40% Glycerol, pH 7.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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