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Recombinant Human Angiopoietin-like 8/ANGPTL8 (22-198) Protein (RPCB1762)

SKU:
RPCB1762
Size:
10µg
Tag:
N-hFC
Reactivity:
Human
Expression Host:
HEK293 cells
$299

Description

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Product Name:Recombinant Human Angiopoietin-like 8/ANGPTL8 (22-198) Protein
SKU:RPCB1762
Size:10µg
Tag:N-hFC
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human Angiopoietin-like 8/ANGPTL8 (22-198) Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<1EU/μg
Purity:> 80% as determined by by reducing SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Gene ID:55908

The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it acts as a blood lipid regulator by regulating serum triglyceride levels and possibly by promoting ANGPTL3 cleavage. It interacts with ANGPTL3. It predominantly expressed in liver and also expressed in adipose tissues. The ability of the protein to induce pancreatic beta cell proliferation is promising in diabetes therapy. Betatrophin treatment could supply or replace insulin injections by increasing the number of insulin-producing cells in diabetes.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q6UXH0
Product ImageRecombinant Human Angiopoietin- like 8/ANGPTL8 Protein was determined by SDS-PAGE with Coomassie Blue, showing bands at 54 KDa.

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