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Recombinant Cynomolgus TPBG/5T4 (C-6His)

SKU:
RPES6775
Product Type:
Recombinant Protein
Species:
Monkey
$359
Frequently bought together:

Description

Product Name:Recombinant Cynomolgus TPBG/5T4 (C-6His)
Product Code:RPES6775
Size:10µg
Species:Cynomolgus macaques
Expression Host:HEK293 Cells
Synonyms:5T4 Protein, Human, 5T4AG Protein, Human, M6P1 Protein, Human, WAIF1 Protein, Human
Mol Mass:35.7 kDa
AP Mol Mass:55-80 kDa
Tag:C-6His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Thr35-Ser355
Accession:Q4R8Y9
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

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