Recombinant Cynomolgus FGL1 (C-6His) (RPES6767)
- SKU:
- RPES6767
- Product Type:
- Recombinant Protein
- Species:
- Monkey
Description
| Product Name: | Recombinant Cynomolgus FGL1 (C-6His) |
| Product Code: | RPES6767 |
| Size: | 10µg |
| Species: | Cynomolgus macaques |
| Expression Host: | HEK293 Cells |
| Synonyms: | Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, Angptl4, Farp, Fiaf, Ng27 |
| Mol Mass: | 34.8 kDa |
| AP Mol Mass: | 35 kDa |
| Tag: | C-6His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Bio Activity: | Loaded Cynomolgus LAG-3-Fc on Protein A Biosensor, can bind Cynomolgus FGL1-His with an affinity constant of 28.6nM as determined in BLI assay. |
| Sequence: | Leu23-Ile312 |
| Accession: | A0A2K5X990 |
| Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation: | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Trehalose, 300mM NaCl, 50% Glycerol, 0.05% Tween 80, pH 8.5 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the s |
| Reconstitution: | Not Applicable |
| Background: | Hepassocin, also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1), is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 . |
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