Recombinant Cynomolgus CTLA-4/CD152 Protein (RPCB1945)
- SKU:
- RPCB1945
- Size:
- 100µg
- Tag:
- C-His
- Reactivity:
- Cynomolgus
- Expression Host:
- HEK293 cells
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Description
| Product Name: | Recombinant Cynomolgus CTLA-4/CD152 Protein |
| SKU: | RPCB1945 |
| Size: | 100µg |
| Tag: | C-His |
| Reactivity: | Cynomolgus |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Cynomolgus CTLA-4/CD152 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | Less than 1EU per μg by the LAL method. |
| Purity: | > 95% as determined by Tris-Bis PAGEï¼›> 95% as determined by HPLC |
| Gene ID: | 102115124 |
CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | G7PL88-1 |
 | Cynomolgus CTLA-4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
 | The purity of Cynomolgus CTLA-4 is greater than 95% as determined by SEC-HPLC. |
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