Recombinant Cynomolgus Beta-2-Microglobulin/B2M Protein (RPCB2170)
- SKU:
- RPCB2170
- Size:
- 100µg
- Tag:
- C-His
- Reactivity:
- Cynomolgus
- Expression Host:
- HEK293 cells
Description
| Product Name: | Recombinant Cynomolgus Beta-2-Microglobulin/B2M Protein |
| SKU: | RPCB2170 |
| Size: | 100µg |
| Tag: | C-His |
| Reactivity: | Cynomolgus |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Cynomolgus Beta-2-Microglobulin/B2M Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | Less than 1EU per μg by the LAL method. |
| Purity: | > 95% as determined by Tris-Bis PAGEï¼›> 95% as determined by HPLC |
| Gene ID: | 712428 |
The genetic and functional analysis of β2-microglobulin (B2M), a component of the HLA class-I complex.Acquired homozygous loss of B2M that caused lack of cell-surface HLA Class I expression in the tumor and a matched patient-derived xenograft (PDX). Downregulation of B2M was also found in two additional PDXs established from ICI-resistant tumors.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | Q8SPW0 |
 | Cynomolgus B2M on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
 | The purity of Cynomolgus B2M is greater than 95% as determined by SEC-HPLC. |
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