The REC8 Polyclonal Antibody (CAB15002) is an essential tool for researchers studying REC8, a key protein involved in meiotic cell division. This antibody, produced in rabbits, exhibits high reactivity and specificity towards REC8 in human samples, making it suitable for Western blot applications. By binding to the REC8 protein, this antibody allows for precise detection and analysis in various cell types, providing valuable insights into meiotic processes and chromosomal segregation.REC8 is crucial for the proper alignment and segregation of chromosomes during meiosis, ensuring the accurate distribution of genetic material to daughter cells.
Dysregulation of REC8 can lead to errors in chromosome segregation, resulting in genetic abnormalities and infertility. Research into REC8 function is essential for understanding meiotic division and genetic stability, with implications for fertility treatments and reproductive health.Overall, the REC8 Polyclonal Antibody is a versatile tool for investigating REC8 function and meiotic processes, offering valuable insights into chromosome segregation and genetic stability. Its reliable performance and specificity make it a valuable asset for researchers in the fields of biology, genetics, and reproductive medicine.
Product Name:
REC8 Rabbit Polyclonal Antibody
SKU:
CAB15002
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 194-561 of mouse REC8 (NP_064386.2).
Predicted to enable chromatin binding activity. Acts upstream of or within several processes, including gamete generation; seminiferous tubule development; and synaptonemal complex assembly. Located in kinetochore; lateral element; and male germ cell nucleus. Part of nuclear meiotic cohesin complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human REC8 (REC8 meiotic recombination protein).
Purification Method:
Affinity purification
Gene ID:
56739
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat testis, using REC8 Rabbit pAb (CAB15002) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
