The RDM1 Polyclonal Antibody (CAB6845) is a valuable tool for researchers studying the RDM1 protein, a key player in DNA replication and repair processes. This antibody, produced in rabbits, is highly specific to human samples and has been extensively validated for use in Western blot applications. By targeting the RDM1 protein, this antibody allows for precise detection and analysis in various cell types, making it ideal for research in molecular biology, cancer biology, and genetic disorders.
RDM1 is essential for maintaining genomic stability and integrity by coordinating DNA replication and repair mechanisms. Dysregulation of RDM1 has been implicated in various diseases, including cancer and developmental disorders. Investigating the function of RDM1 with this polyclonal antibody can provide important insights into the molecular mechanisms underlying these conditions, potentially leading to the development of novel therapeutic strategies in the future.
Product Name:
RDM1 Rabbit Polyclonal Antibody
SKU:
CAB6845
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 125-284 of human RDM1 (NP_663629.1).
This gene encodes a protein involved in the cellular response to cisplatin, a drug commonly used in chemotherapy. The protein encoded by this gene contains two motifs: a motif found in RAD52, a protein that functions in DNA double-strand breaks and homologous recombination, and an RNA recognition motif (RRM) that is not found in RAD52. The RAD52 motif region in RAD52 is important for protein function and may be involved in DNA binding or oligomerization. Alternatively spliced transcript variants encoding different isoforms have been reported.
Purification Method:
Affinity purification
Gene ID:
201299
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RDM1 antibody (CAB6845) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
