RDH5 Rabbit Polyclonal Antibody (CAB8055)
- SKU:
- CAB8055
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | RDH5 Rabbit Polyclonal Antibody |
SKU: | CAB8055 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-318 of human RDH5 (NP_002896.2). |
Sequence: | LPAS NAFV FITG CDSG FGRL LALQ LDQR GFRV LASC LTPS GAED LQRV ASSR LHTT LLDI TDPQ SVQQ AAKW VEMH VKEA GLFG LVNN AGVA GIIG PTPW LTRD DFQR VLNV NTMG PIGV TLAL LPLL QQAR GRVI NITS VLGR LAAN GGGY CVSK FGLE AFSD SLRR DVAH FGIR VSIV EPGF FRTP VTNL ESLE KTLQ ACWA RLPP ATQA HYGG AFLT KYLK MQQR IMNL ICDP DLTK VSRC LEHA LTAR HPRT RYSP GWDA KLLW LPAS YLPA SLVD AVLT WVLP KPAQ AVY |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | RDH1; 9cRDH; SDR9C5; HSD17B9; RDH5 |
Positive Sample: | A-549,BT-474,Mouse liver,Mouse kidney,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum lumen, Membrane, Peripheral membrane protein. |
Calculated MW: | 35kDa |
Observed MW: | 38kDa |
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.
Purification Method: | Affinity purification |
Gene ID: | 5959 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |