The RDH11 Polyclonal Antibody (CAB18454) is specifically designed for research involving RDH11, a protein involved in the metabolism of retinoids and potentially implicated in various diseases, including cancer and eye disorders. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to RDH11, the antibody enables accurate detection and analysis of this key protein in different cell types, making it an ideal tool for studies in metabolism, cancer biology, and ophthalmology.RDH11, a retinol dehydrogenase enzyme, plays a crucial role in the conversion of vitamin A into its active form, retinoic acid, which is essential for various biological processes, including cell growth, differentiation, and vision.
Dysregulation of RDH11 has been associated with diseases such as cancer and retinal degeneration, highlighting the importance of studying its function and potential therapeutic implications. Investigating the role of RDH11 in disease pathogenesis may provide valuable insights for the development of novel treatment strategies targeting retinoid metabolism.
Product Name:
RDH11 Rabbit Polyclonal Antibody
SKU:
CAB18454
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 70-145 of human RDH11 (NP_057110.3).
Enables NADP-retinol dehydrogenase activity. Involved in cellular detoxification of aldehyde and retinoid metabolic process. Acts upstream of or within retinal metabolic process. Located in endoplasmic reticulum membrane.
Purification Method:
Affinity purification
Gene ID:
51109
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RDH11 Rabbit pAb (CAB18454) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
