The RCC2 Polyclonal Antibody (CAB13105) is a valuable tool for researchers studying the RCC2 protein, a key regulator of cell division and migration. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RCC2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and cancer research.RCC2, also known as regulator of chromosome condensation 2, plays a crucial role in the proper organization and segregation of chromosomes during cell division.
Dysregulation of RCC2 has been implicated in cancer development and progression, making it a promising target for therapeutic interventions. Research into the function and mechanisms of RCC2 is essential for advancing our understanding of cancer biology and identifying potential treatment strategies.Overall, the RCC2 Polyclonal Antibody offers researchers a reliable tool for investigating the role of RCC2 in cellular processes and disease pathogenesis, opening up new possibilities for advancing cancer research and drug development.
Product Name:
RCC2 Rabbit Polyclonal Antibody
SKU:
CAB13105
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 323-522 of human RCC2 (NP_001129676.1).
The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer.
Purification Method:
Affinity purification
Gene ID:
55920
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RCC2 Rabbit pAb (CAB13105) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
